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venture capital firm investing in Seed to Series C B2B technology companies, providing operational support.
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Asymmetric Capital Partners is an early-stage venture capital firm jointly based in Boston, Massachusetts, and New York, New York, that invests in Seed to Series C stage B2B technology startups. The firm focuses its equity investments on enterprise software, digital health, online marketplaces, and the broader digitization of legacy industries. Operating with a capped fund size model to maintain an operator-centric approach, the organization closed an oversubscribed $105 million debut fund in late 2021 backed by family offices and high-net-worth individuals. The firm provides strategic go-to-market and hiring support to its portfolio companies through an investment team that includes partners Sarah Unger Biggs and Sam Clayman. The staff also features former operators with direct experience scaling prominent technology enterprises such as Klaviyo and Catalant Technologies. Asymmetric Capital Partners was founded in late 2020 by Rob Biederman.
Key people at Asymmetric Capital Partners.
Key people at Asymmetric Capital Partners.
Asymmetric Capital Partners is an early-stage technology investment firm founded in 2021, focused on backing founders with conviction, concentrated ownership, and operational support. The firm invests primarily in Pre-seed through Series A rounds, targeting disruptive, technology-driven companies in sectors such as vertical software for legacy industries, healthcare IT and services, and technology-enabled SMB consolidations (rollups). Asymmetric emphasizes a hands-on, operator-led investment philosophy, partnering closely with founders to refine ideas, build go-to-market strategies, recruit key executives, and pursue acquisitions. With over $240 million in assets under management and nearly 90 companies backed, the firm has established itself as a value-added investor that supports startups through critical growth phases[1][2][4].
Founded in 2021, Asymmetric Capital Partners was created by a team of former founders and operators who bring deep investing experience combined with hands-on operational expertise. The founding partners have backgrounds in building, scaling, and acquiring companies, which informs their approach to venture capital as active, thoughtful partners rather than passive investors. The firm’s evolution has been marked by a focus on high-conviction, concentrated investments in early-stage companies where they can have meaningful influence. Their first fund ranked in the top 5% of its 2021 vintage, and the firm recently closed a $137 million second fund, surpassing its target, reflecting strong support from returning and new institutional investors[1][2][3][4].
Asymmetric Capital Partners rides the wave of digital transformation disrupting legacy industries through software and technology-driven efficiencies. Their timing is critical as many traditional sectors face pressure to modernize, creating fertile ground for startups with innovative vertical software solutions, healthcare IT advancements, and rollup strategies that consolidate fragmented markets. By focusing on early-stage companies with strong technical and domain expertise, Asymmetric influences the ecosystem by enabling founders to challenge entrenched assumptions and build scalable, sustainable businesses. Their operator-led model also helps bridge the gap between capital and execution, fostering startups that can endure and lead long-term industry shifts[2][4].
Looking ahead, Asymmetric Capital Partners is positioned to deepen its influence by continuing to back founders with contrarian insights and operational rigor. The firm’s emphasis on concentrated ownership and active partnership aligns well with emerging trends in vertical software, healthcare innovation, and market consolidation. As digital disruption accelerates across legacy sectors, Asymmetric’s approach of blending investment discipline with hands-on support will likely yield further successful outcomes and exits. Their growing assets under management and strong LP relationships suggest sustained confidence in their model, with potential expansion into adjacent sectors or later-stage opportunities as portfolio companies mature[1][2][3][4].
This forward-looking stance ties back to Asymmetric’s founding mission: to be a different kind of venture capital firm that partners deeply with founders to create truly asymmetric returns through conviction, concentration, and operational excellence.
Asymmetric Capital Partners has more than 26 tracked investments across 24 companies. The latest tracked deal is $10.0M Series A in Voomi Supply in March 2026.